This search combines search strings from the content search (i.e. "Full Text", "Author", "Title", "Abstract", or "Keywords") with "Article Type" and "Publication Date Range" using the AND operator.
Beilstein J. Org. Chem. 2014, 10, 2332–2337, doi:10.3762/bjoc.10.242
Graphical Abstract
Scheme 1: The 3-component coupling strategy.
Figure 1: Synthesis of trienes 5–7.
Scheme 2: Synthesis of polyols 10–14 in one-, two-pot sequential protocols.
Scheme 3: Synthesis of polyols 17–21 in one-, two-pot sequential protocols.
Beilstein J. Org. Chem. 2014, 10, 2087–2088, doi:10.3762/bjoc.10.217
Beilstein J. Org. Chem. 2012, 8, 1293–1302, doi:10.3762/bjoc.8.147
Figure 1: Biologically active benzofused sultams.
Scheme 1: Proposed library generation by microwave-assisted intermolecular SNAr diversification reaction.
Scheme 2: Utilization of a reaction pairing strategy for the synthesis of benzoxathiazocine 1,1-dioxides core...
Figure 2: Benzoxathiazocine 1,1-dioxides 1–8 and amine library building blocks {1–10}.
Figure 3: (i) Simple cartoon of the library compounds, with a core of MW ~ 80, based on Lipinski’s rules (MW ...
Figure 4: Distribution of 80 compounds (colored spheres) relative to the set of 771 known orally available dr...
Figure 5: Comparison of a small set of our representative compounds versus two sultams synthesized by our gro...
Figure 6: Three representative compounds with high QED values.
Figure 7: Representation of Z-scores for the 80 compounds.